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Accurate codon recognition by tRNAs is necessary for correct translation of mRNA nucleotide sequence into the protein sequence. Here, different factors contributing to the correct codon reading by tRNAs are reviewed. In particular, the monitoring of codon-anticodon helix geometry by 16S rRNA bases, and the role of tRNA sequence elements and posttranscriptional modifications for modulating codon-anticodon interactions are discussed.
Publication order reference
Tomasz Pawlowski, Instytut Dendrologii, Polska Akademia Nauk, ul. Parkowa 5, 62-035 Kornik, Poland