The role of free radicals in pathogenesis of systemic sclerosis
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This article reviews the current concept in the ethiology and pathogenesis of systemic sclerosis. It is suggested that free radicals play a crucial role in pathomechanisms of scleroderma. In addition, the influence of some environmental agents (silica, bleomycin, aalcohol, toxic oil) on free radical production and subsequent induction of scleroderma or scleroderma-like syndrome is also described.
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K.Komosinska, ul. Piastow 24/78, 40-868 Katowice, Poland