PL EN


Preferences help
enabled [disable] Abstract
Number of results
1992 | 30 | 2 | 111-126
Article title

Calcium accumulation in synapses of the rat hippocampus after cerebral ischemia

Title variants
Languages of publication
EN
Abstracts
EN
The ultrastructural localization of calcium deposits in the synapses of rat hippocampus after 10 min global cerebral ischemia was evaluated. Oxalate-pyroantimonate technique was applied. After 24 hours of postischemic recirculation enhancement of intracellular (pre- and postsynaptic parts) and extracellular (synaptic clefts) calcium deposits was found in great proportion of synapses in CA1 sector. Abundant Ca-precipitates appeared specially in synaptics clefts and in the postsynaptic parts near synaptic densities. Increased calcium deposits in some changed mitochondria were also observed, The results presented in this paper suggest synaptic modulation of calcium homeostasis, disturbed after ischemic incident. Presence of Ca-precipitates in synaptic clefts and postsynaptic parts seems to be a sensitive indicator of increased calcium influx from the extracellular to the intracellular compartments.
Keywords
Publisher

Year
Volume
30
Issue
2
Pages
111-126
Physical description
Contributors
References
Document Type
article
Publication order reference
Barbara Gajkowska
Identifiers
YADDA identifier
bwmeta1.element.element-from-psjc-e2f69dc1-1f15-370e-9a9e-ec0de6b9e266
JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.