Role of the adaptins, dynamin-like GTP-ases and Rab proteins in metabolic disorders and various infections

• Authors: M. Kierczak , L. Surmacz , J. Wiejak , E. Wyroba
• Languages of publication: PL

Abstracts

EN

Numerous metabolic and genetic diseases are due to mutations in adaptins, dynamin-like GTP-ases or disorders in trafficking machinery mediated by Rab proteins. A great number of pathogenes including viruses (HIV, SIV), bacteria and protozoa use various elements of endocytic/trafficking machinery to get into the host cells and to make their infection successful. Their different strategies are discussed.

Keywords

EN

ADAPTIN; HIV; METABOLIC DISORDER; RAB PROTEIN; VIRUS INFECTION

Discipline

• EXPERIMENTAL_BIOLOGY_&_MEDICINE: EXPERIMENTAL BIOLOGY & MEDICINE

• Publisher: Index Copernicus International
• Journal: Postępy Higieny i Medycyny Doświadczalnej
• Year: 2003
• Volume: 57
• Issue: 6
• Pages: 727-737

Contributors

author

M. Kierczak

author

L. Surmacz

author

J. Wiejak

author

E. Wyroba

• Document Type: ARTICLE
• Publication order reference: E. Wyroba, Instytut Biologii Doswiadczalnej im. M.Nenckiego PAN, ul. Pasteura 3, 02-093 Warsawa, Poland