Role of the adaptins, dynamin-like GTP-ases and Rab proteins in metabolic disorders and various infections
Languages of publication
Numerous metabolic and genetic diseases are due to mutations in adaptins, dynamin-like GTP-ases or disorders in trafficking machinery mediated by Rab proteins. A great number of pathogenes including viruses (HIV, SIV), bacteria and protozoa use various elements of endocytic/trafficking machinery to get into the host cells and to make their infection successful. Their different strategies are discussed.
Publication order reference
E. Wyroba, Instytut Biologii Doswiadczalnej im. M.Nenckiego PAN, ul. Pasteura 3, 02-093 Warsawa, Poland