As of 1 April 2026, the PSJD database will become an archive and will no longer accept new data. Current publications from Polish scientific journals are available through the Library of Science: https://bibliotekanauki.pl
The review presents the properties and significance of soluble forms of Tumor Necrosis Factor-alfa receptors in physiology and pathology of human organism. Special attention was turned to the possibility of practical application of those forms of the receptors in the therapy of diseases caused by excessive activity of TNF-alfa.