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1992 | 40 | 2 | 145-150
Article title

In vitro cytostatic activity of some amino acid 4-N-substituted cytosines

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Languages of publication
EN
Abstracts
EN
Cytotoxicity of 22 amino acid 4-N-substitued cytosine derivatives was studied on KB and HeLa human tissue cultures. The secondary modification of tryptamine substituent seems to be a determining factor of the cytotoxic activity of 4-N-pyrimidinyl amino acids. The activity of the investigated compounds was inversely dependent on their solubility limited by the results of the solubility-activity relationship analysis.
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Year
Volume
40
Issue
2
Pages
145-150
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Document Type
article
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YADDA identifier
bwmeta1.element.element-from-psjc-d53b95bb-1d18-38ec-828f-1b01a92e9741
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