Fraction of spleen cells responsible for suppresion of cellular immune response to SRBC in mice treated with outer membrane proteins of Shigella

• Authors: Anna Czarny , Danuta Witkowska , Marian Mulczyk
• Languages of publication: EN

Abstracts

EN

Effect of splenocytes isolated from mice immunized with suppressive dose of OMP rfom Shigella on delaed hipersensivity, induced in mice with sheep red blood cells was investigated. Only the population of T lymphocytes was found to suppress the delayed hypersensitivity, as measured by the footpad reaction. The results suggest that OMP of Shigella are able to induce in the spleen of animals active T cells which are responsible for the suppression of cellular response induced by SRBC.

Keywords

EN

IMMUNE RESPONSE; MOUSE; SHIGELLA; SPLEEN CELL

Discipline

• IMMUNOLOGY: IMMUNOLOGY

• Publisher: Ludwik Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences
• Journal: Archivum Immunologiae et Therapiae Experimentalis
• Year: 1992
• Volume: 40
• Issue: 2
• Pages: 135-137

Contributors

author

Anna Czarny

author

Danuta Witkowska

author

Marian Mulczyk

• Document Type: article