Influence of cysteine on mechlorethamine-induced chromosomal aberrations in cultured human lymphocytes

• Authors: A. Blaszczyk
• Languages of publication: EN

Abstracts

EN

The aim of the present paper was to find out by in vitro chromosomal aberration test using human lumphocytes whether cysteine has anticlastogenic properties towards a well-known mutagen - mechlorethamine.The lymphocytes tested were obtained rom three healthy donors.Two doses of cysteine and three doses of mechlorethamine were tested.It was found that cysteine had anticlastogenic properites and that it reduced the number of mrthaphase with chromosomal aberrations induced by mechlorethamine.

Keywords

EN

ANTICLASTOGENS; CHROMOSOMAL ABERRATION; CYSTEINE; IN VITRO; MECHLORETHAMINE; MUTAGENICITY

Discipline

• GENETICS: GENETICS

• Publisher: Institute of Plant Genetics, Polish Academy of Sciences
• Journal: Journal of Applied Genetics
• Year: 1995
• Volume: 36
• Issue: 4
• Pages: 389-393

Contributors

author

A. Blaszczyk

• Document Type: article
• Publication order reference: A.Blaszczyk