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2003 | 57 | 1 | 3-17
Article title

Viral infections in children after allogenic stem cells transplantation

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Languages of publication
PL
Abstracts
EN
Allogeneic hematopoietic cell transplantation (alloHCT) is the treatment of choice for various pediatric malignancies and nonmalignant diseases. The most prominent complication of allotransplantation is graft vs host disease (GvHD). The treatment of GvHD influence negatively function of immune system and increase risk of bacterial, fungal and viral infections. Clinical symptoms of viral infection may mimic GvHD and lead to inappropriate treatment. Human ctomegalovirus (CMV, Herpesviridae) has been recognized as most important viral pathogen after alloHCT. Increasing number of procedures, especially from alternative donors, requiring more intensive immunosuppression, led to identification more viral pathogens causing transplant related mortality and morbidity. Among them are adenoviruses (ADV, Adenoviridae), BK and JC viruses (Papovaviridae) and human herpes virus 6 (HHV-6, Herpesviridae). Frequency of complications caused by those pathogens is higher in children then in adults.
Publisher

Year
Volume
57
Issue
1
Pages
3-17
Physical description
Contributors
author
author
References
Document Type
ARTICLE
Publication order reference
K. Rybka, Instytut Immunologii i Terapii Doswiadczalnej PAN, Ul. R.Weigla 12, 53-114 Wroclaw, Poland
Identifiers
YADDA identifier
bwmeta1.element.element-from-psjc-c2a5acb6-2ca2-3271-9124-1510abf0ca54
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