The effect of calcium channel blockade during electroconvulsive treatment on cerebral cortical adrenoceptor subpopulations in the rat

• Authors: Lucyna Antkiewicz-Michaluk , Jerzy Michalik , Irena Romanska , Jerzy Vetulani
• Languages of publication: EN

Abstracts

EN

Chronic administration of nifedipine (5 mg/kg/day for 10 days) induced some biochemical effects consistent with those of antidepressants: a significant depression in cortical alfa2-adrenoceptor density and reduction of beta-adrenoceptor affinity; nifedipine co-administration with electroconvulsive treatment potentiated the beta-downregulatory effect of the latter.

Keywords

EN

ALPHA1-ADRENOCEPTOR   ALPHA2-ADRENOCEPTOR   BETA-ADRENOCEPTOR   NIFEDIPINE  

Discipline

• PHARMACOLOGY: PHARMACOLOGY

• Publisher: Institute of Pharmacology, Polish Academy of Sciences
• Journal: Polish Journal of Pharmacology
• Year: 1993
• Volume: 45
• Issue: 2
• Pages: 197-200
• Document Type: communication