Inhibitors of neoangiogenesis in antitumor therapy

• Authors: A. Opolski , J. Wietrzyk
• Languages of publication: EN

Abstracts

EN

The role of angiogenesis in tumor growth and metastasis is discussed. The endogenous activators and inhibitors of tumor angiogenesis are presented and their mechanisms of action are reviewed. An overview on angiogenesis as a new potential targed of antitumor therapy is described. The clinical trials of various antiangiogenic agents are briefly summarized and their differential mechanisms of action are discussed.

Keywords

EN

ANTIANGIOGENIC TREATMENT   ANTITUMOR THERAPY   INHIBITOR   METASTASIS   TUMOR ANGIOGENESIS  

Discipline

• EXPERIMENTAL_BIOLOGY_&_MEDICINE: EXPERIMENTAL BIOLOGY & MEDICINE

• Publisher: Index Copernicus International; Ludwik Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences
• Journal: Postępy Higieny i Medycyny Doświadczalnej
• Year: 2001
• Volume: 55
• Issue: 3
• Pages: 369-385
• Document Type: ARTICLE
• Publication order reference: A. Opolski, Instytut Immunologii i Terapii Doswiadczalnej PAN, ul. R.Weigla 12, 53-514 Wroclaw, Poland