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Availability of fully sequenced genomes contributes to the development of new science named phylogenomics which opens new possibilities of phylogenetic analyses and study of genome evolution based on the whole information coded in genomic DNA. The advantages and disadvantages of the new methods are described. Despite many phenomena such as lineage-specific gene loss, gene duplication and horizontal gene transfer disturbing phylogenetic analyses, the new methods are able to extract some phylogenetic signals in the analysed genomes and construct reliable phylogenetic trees. The genome-based studies support not only the three-domain concept of Tree of Life but they identify previously undetected major clades of prokaryotes as well.
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102-117
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REVIEW
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Maciej Sobczynski, Zaklad Genomiki, Instytut Genetyki i Mikrobiologii, Uniwersytet Wroclawski, ul. Przybyszewskiego 63/77, 51-148 Wroclaw, Poland
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bwmeta1.element.element-from-psjc-bc82aeff-32ed-3bff-a12a-798180655393