Gelatine is defined as a mixture of polypeptides obtained by partial non-enzymatic hydrolysis of collagen contained in bones and skins mainly bovines and/or pigs after the following treatments: degreasing, acid treatment, and/or alkaline treatment, washing, filtration, ion exchange and sterilization. Gelatine is produced for consumption and industrial purposes, and it is widely used as a component of various products. Scrapie and BSE are extremely resistant to various physical and chemical treatments. The gelatine can only be produced safely from healthy animals. European Community as well as FDA in the USA have paid close attention to this problem and issued special reports and rules on that matter.