Screening methods of industrial strain mutants

• Authors: E. Galas , E. Kwapisz , J. Polak
• Languages of publication: PL

Abstracts

EN

The screening methods used for improvement of industrial strains are presented.Two general categories of methods have been distinguished: random screening and rational screening.Major techniques employed in rational screening are based on the selection of auxotropic mutants, reverants of non-producers, strain resistant to some factors like toxic analogues of metabolism intermediates, induction and catabolite regression or end-product inhibition, mutants with modified cell wall permeability and microorganisms tolerating somenutrients and precursors of secondary metabolites.

Keywords

EN

INDUSTRIAL STRAIN; MICROORGANISM; SCREENING; SELECTION; STRAIN IMPROVEMENT

Discipline

• BIOTECHNOLOGY: BIOTECHNOLOGY

• Publisher: Committee of Biotechnology, Polish Academy of Sciences
• Journal: Biotechnologia
• Year: 1995
• Issue: 3
• Pages: 104-119

Contributors

author

E. Galas

author

E. Kwapisz

author

J. Polak

• Document Type: article
• Publication order reference: E.Kwapisz