Down-regulating effect on cellular immunity of the NSF17 factor produced by murine neonatal spleen cells fused with BW 5147 Thymoma cells

• Authors: Maria Bubak-Sator , Oldrich Machala , Marta Kubera , Bozena Mazur-Kolecka , Anna Skowron-Cendrzyk
• Languages of publication: EN

Abstracts

EN

The non-specific factor NSF17 produced by mouse newborn splenocytes fused with BW 5147 thymona cells was tested in vivo for its immunosuppressive activity. NSF17 administered i.p. in a single dose into adult mice significantly decreased the PHA-induced proliferative response of lymphocytes, regional graft-versus-host reaction, and delayed-type hypersensitivity.

Keywords

EN

GVH REACTION; SUPPRESSOR FACTOR

Discipline

• EXPERIMENTAL_BIOLOGY_&_MEDICINE: EXPERIMENTAL BIOLOGY & MEDICINE

• Publisher: Institute of Systematics and Evolution of Animals, Polish Academy of Sciences
• Journal: Folia Biologica
• Year: 1992
• Volume: 40
• Issue: 1-2
• Pages: 79-82

Contributors

author

Maria Bubak-Sator

author

Oldrich Machala

author

Marta Kubera

author

Bozena Mazur-Kolecka

author

Anna Skowron-Cendrzyk

• Document Type: article