This work reports the results on bioconversion of two lignocellulose wastes, i.e. wheat waste and faba bean hulls by fungi T. reesei and A. niger. The efficiency of lignocelluloses biodegradation after culturing the fungi was determined on the basis of the reduction of fibre content in the substrates, increase of protein in the preparations obtained, and the yield of protein biosynthesis. The experiments included the determination of the effect of various technological variables on the process intensification, i.e. method of culturing (shake- or surface culture), type of culture (single strains or mixed culture), raw material pre-treatment (physico-chemical or enzymatic treatment), and additional sources of carbon in the medium, inducing the biosynthesis of cellulases. In selected preparations after culturing the fungi, the changes in the composition of dietary fibre (soluble, SDF and insoluble, IDF) and simple sugars in the IDF fraction were analysed in detail.