The role of Porphyromonas gingivalis proteinases in periodontitis

• Authors: J. Polanowska , A. Polanowski
• Languages of publication: PL

Abstracts

EN

Periodontitis, an inflammation of periodontal tissues, exists in several clinical forms. The most common one is adult periodontitis with Porphyromonas gingivalis, a Gram-negative anaerobic rod, being generally regarded as the major pathogen involved in this disease. This organism produces a large quantity of proteolytic enzymes, as virulence factors, which are considered to play a crucial role in its pathogenecity. These enzymes are involved in both destruction of periodontal tissues and interrupting host-defence mechanisms through the degradation of immunoglobulins and complement factors leading eventually to disease progression.

Keywords

EN

PERIODONTITIS; PORPHYROMONAS GINGIVALIS

Discipline

• EXPERIMENTAL_BIOLOGY_&_MEDICINE: EXPERIMENTAL BIOLOGY & MEDICINE

• Journal: Postępy Higieny i Medycyny Doświadczalnej
• Year: 1997
• Volume: 51
• Issue: 2
• Pages: 149-169

Contributors

author

J. Polanowska

author

A. Polanowski

• Document Type: article
• Publication order reference: J.Polanowska, ul. Tamka 2, 50-137 Wroclaw, Poland