Microorganisms in stereoselective organic synthesis
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This paper deals with the use of microorganisms for the synthesis of homochiral compounds. The influence of various factors on the efficiency of biotransformation employing whole cells is discussed. The author?s attention was focused on stereochemistry of reaction since the knowledge of its rules allows to control the stereoselectivity and productivity of biotransformation. Some interesting examples of best documented bioreduction and biooxidation reactions were selected and are reported in this article.
Publication order reference
W. Szeja, Katedra Technologii Chemicznej Wegla i Ropy Naftowej, Politechnika Slaska, ul. B. Krzywoustego 8, 44-101 Gliwice, Poland