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Languages of publication
Abstracts
Leukotrienes, products of the 5-lipoxygenase pathway of arachidonic acid, are pro-inflammatory mediators with various biological activities, including mechanisms relevant to the pathogenesis of bronchoobturation in bronchial asthma. This article reviews the evidence on their role in the pathophysiology of asthma as well as on the efficacy of recently developed antileukotriene agents. Leukotriene receptor antagonists and synthesis of inhibitors show promise as a new pharmacologic approach to the treatment of this disease.
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Year
Volume
Issue
Pages
499-514
Physical description
Contributors
author
author
References
Document Type
article
Publication order reference
P. Wojnowski, Klinika Chorob Wewnetrznych i Alergologii AM, ul. Traugutta 57/59, 50-417 Wroclaw, Poland
Identifiers
YADDA identifier
bwmeta1.element.element-from-psjc-a559ede1-b5f2-3d1c-ba6c-b5c2ef7d8a92