Chemical modifications of macromolecules and their use in the preparation of protein antitumor drug conjugates, vaccines and diagnostic reagent

• Authors: J. Boratynski
• Languages of publication: PL

Abstracts

EN

This article reviews high temperature glycation of proteins, and describes some applications of thus recived neoglycoconjugates as vaccines or drug and gene carriers. The use of macromolecules: antibodies, fibrinogen and natural or synthetic polymers as antitumor drug carriers is discussed. Moreover the article presents method for monitoring of proteins modification by glutaraldehyde.

Keywords

EN

MACROMOLECULE; NEOGLYCOCONJUGATE

Discipline

• EXPERIMENTAL_BIOLOGY_&_MEDICINE: EXPERIMENTAL BIOLOGY & MEDICINE

• Publisher: Index Copernicus International
• Journal: Postępy Higieny i Medycyny Doświadczalnej
• Year: 2000
• Volume: 54
• Issue: 1
• Pages: 17-36

Contributors

author

J. Boratynski

• Document Type: ARTICLE
• Publication order reference: J. Boratynski, Instytut Immunologii i Terapii Doswiadczalnej PAN, ul R.Weigla 12, 53-114 Wroclaw, Poland