Oligonucleotide transport across the plasma membrane

• Authors: J. Laski
• Languages of publication: PL

Abstracts

EN

Transport of synthetic oligonucleotides across the plasma membrane of mammlian cells is the one of the major problems in the application of the antisense strategy.Modifications of oligonucleotides may improve their transport and stability in the cell's medium.The therapeutical agents tergeted to intracellular structures and their mechanisms are reviewed.

Keywords

EN

ANTISENSE   ENDOCYTOSIS   MEMBRANE TRANSPORT   METHYLPHOSPHONATE   OLIGONUCLEOTIDE UPTAKE   PHOSPHOROTHIOATE  

Discipline

• BIOTECHNOLOGY: BIOTECHNOLOGY

• Publisher: Committee of Biotechnology, Polish Academy of Sciences
• Journal: Biotechnologia
• Year: 1994
• Issue: 4
• Pages: 40-49
• Document Type: article
• Publication order reference: J.Laski