Quantitative determination of oxidative base damage in DNA

• Authors: T.H. Zastawny
• Languages of publication: PL

Abstracts

EN

Oxidative DNA damage produced by free radicals has been implicated to play a role in mutagenesis, carcinogenesis and aging.There is, therefore, increasing interest in teh development of accurate assays for measuring DNA base damage.Such assays should help to define the biological consequences of oxidative DNA modifications and to identify enzymatic repair pathways.The present article describes the potential usefulness of different technique for chemical characterizatoin and quantitation of ixidative modifications in DNA.

Keywords

EN

DNA DAMAGE; OXIDATIVE DAMAGE

Discipline

• EXPERIMENTAL_BIOLOGY_&_MEDICINE: EXPERIMENTAL BIOLOGY & MEDICINE

• Journal: Postępy Higieny i Medycyny Doświadczalnej
• Year: 1995
• Volume: 49
• Issue: 5
• Pages: 609-630

Contributors

author

T.H. Zastawny

• Document Type: article
• Publication order reference: T.H.Zastawny