Pilot plant and industrial systems for animal cell cultivation. II. Anchorage independent cell cultures
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In the last decade fast development of modern cell culture techniques is observed. Some new high performance cell culture bioreactors are being designed and tested. These reactors are usually configurated with cell separators to cell recycling. As separators, microfilters, ultrafilters, continuous flow centrifuges and settlers are proposed. The main systems allowing to carry out the high cell density cultures and numerous technological applications of these systems are presented in this review.
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