Application of insect virus - baculovirus AcNPV in the expression of foreign genes

• Authors: Grazyna Kochan , Boguslaw Szewczyk
• Languages of publication: PL

Abstracts

EN

Baculovirus vectors are very useful in producing high levels of proteins. This system yields recombinant proteins similar to their original counterparts. Expression of foreign genes occurs in infected cells which provide a suitable environment for post-translational modifications and folding of the protein product. The size of baculovirus genome allows to insert large DNA segments (up to 25kb). Constructions of recombinant baculoviruses are very simple and need minimum of viral manipulation.

Keywords

EN

BACULOVIRUS; INSECT VIRUS; RECOMBINANT PROTEIN

Discipline

• BIOTECHNOLOGY: BIOTECHNOLOGY

• Publisher: Committee of Biotechnology, Polish Academy of Sciences
• Journal: Biotechnologia
• Year: 1993
• Issue: 2
• Pages: 69-75

Contributors

author

Grazyna Kochan

author

Boguslaw Szewczyk

• Document Type: article