The effect of thymic hormones/TFX/ on lymphocyte subpopulations and proliferation after maximal physical effort

• Authors: Henryk Tchorzewski , Krzysztof Zeman , Roman Lewicki , Ewa Fornalczyk-Wachowska , Aleksandra Golinska , Jerzy Kantorski , Ewa Majewska , Lech Pokoca
• Languages of publication: EN

Abstracts

EN

The studies were performed on healthy well-trained cyclists. Maximal physical exercise was performed on a Monark bicycle ergometer according to individual schemes. Heart rate amounting to about 200 bts/min and oxygen consumption stabilization were considered as criteria for maximal physical exercise. In this study we have investigated the effect of short-term stimulation of conditioned sportsmen with thymic hormones and evaluated T cell subsets, DR antigen and transferrin receptor expression as well as mitogen-induced proliferation of lymphocytes before and after maximal physical effort. The results suggest that intensive physical exercise may be responsible for transient decrease of CD4/CD8 ratio and mitogen responsiveness, and increase of mononuclear cells number bearing HLA DR + and CD71 antigens. These changes were modified by the treatment with thymic hormones.

Keywords

EN

LYMPHOCYTE; PHYSICAL EFFORT; PROLIFERATION; SUBPOPULATION; THYMIC HORMONE

Discipline

• IMMUNOLOGY: IMMUNOLOGY

• Publisher: Ludwik Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences
• Journal: Archivum Immunologiae et Therapiae Experimentalis
• Year: 1992
• Volume: 40
• Issue: 2
• Pages: 157-162

Contributors

author

Henryk Tchorzewski

author

Krzysztof Zeman

author

Roman Lewicki

author

Ewa Fornalczyk-Wachowska

author

Aleksandra Golinska

author

Jerzy Kantorski

author

Ewa Majewska

author

Lech Pokoca

• Document Type: article