Synaptic plasticity in the motor cortex

• Authors: G. Hess
• Languages of publication: PL

Abstracts

EN

Horizontally-oriented intracortical connections have been proposed to serve as a substrate for plastic reorganizations of adult motor cortex. N-methyl-D-aspartate (NMDA) receptor-dependent long-term potentiation (LTP) of synaptic efficacy is a candidate mechanism of these reorganizations in mammalian species ranking from rats to humans. The acquisition of a motor skill is accompanied by increased strength of synaptic connections within adult rat primary motor cortex, most likely due to LTP-like mechanisms.

Keywords

EN

MOTOR CORTEX   SYNAPTIC PLASTICITY  

Discipline

• EXPERIMENTAL_BIOLOGY_&_MEDICINE: EXPERIMENTAL BIOLOGY & MEDICINE

• Publisher: Index Copernicus International; Ludwik Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences
• Journal: Postępy Higieny i Medycyny Doświadczalnej
• Year: 2002
• Volume: 56
• Issue: 3
• Pages: 383-391
• Document Type: ARTICLE
• Publication order reference: G. Hess, Instytut Farmakologii PAN, ul. Smetna 12, 31-343 Krakow, Poland