Leukotrienes ? mediators of inflammation

• Authors: G. Woszczek , R. Pawliczak , M.L. Kowalski
• Languages of publication: PL

Abstracts

EN

Leukotrienes are biologically active metabolites derived from arachidonic acid playing an important role in inflammatory responses. There are two main groups of leukotrienes: dihydroxy-leukotrienes (LTB4) and cysteinyl-leukotrienes (LTC4, LTD4, LTE4). By activating specific G-protein coupled receptors, leukotrienes take part in immune responses, like activation and chemotaxis of leukocytes. Several studies have shown that leukotrienes may play a significant role in pathomechanisms of inflammatory diseases of human airways, skin, digestive tract and heart.

Keywords

EN

IMMUNE RESPONSE; INFLAMMATION; LEUKOTRIENE; LEUKOTRIENE RECEPTOR

Discipline

• EXPERIMENTAL_BIOLOGY_&_MEDICINE: EXPERIMENTAL BIOLOGY & MEDICINE

• Journal: Postępy Higieny i Medycyny Doświadczalnej
• Year: 2003
• Volume: 57
• Issue: 5
• Pages: 593-610

Contributors

author

G. Woszczek

author

R. Pawliczak

author

M.L. Kowalski

• Document Type: ARTICLE
• Publication order reference: G. Woszczek, Katedra i Zaklad Immunologii Klinicznej UM, ul. Pomorska 251, 92-213 Lodz, Poland