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2003 | 51 | 4 | 231-236
Article title

Are NKT cells essential for endotoxic shock?

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Languages of publication
EN
Abstracts
EN
Endotoxic shock is a major health threat caused by Gram-negative bacteria and their unique cell wall component, lipopolysaccharide which induces exaggerated production of proinflammatory cytokines. Although macrophages play a central role in the pathogenesis of endotoxic shock, NK1+ cells are also involved in this mechanism. NK1+ cells comprise two major populations, namely NK cells and NKT cells. It remains, however, elusive whether either NK cells, NKT cells or both are involved in induction of endotoxic shock. This review will focus on the relative contribution of these NK1+ cells to the pathogenesis of endotoxic shock.
Publisher

Year
Volume
51
Issue
4
Pages
231-236
Physical description
Contributors
author
References
Document Type
REVIEW
Publication order reference
M. Emoto, Department of Immunology, Max-Planck-Institute for Infection Biology, Berlin, Germany
Identifiers
YADDA identifier
bwmeta1.element.element-from-psjc-92143b01-5872-3f2f-a3ca-604b162f333c
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