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Number of results
1995 | 49 | 3 | 433-444

Article title

Role glyoxales and methyglyoxal in cell proliferation and differentiation

Title variants

Languages of publication

PL

Abstracts

EN
The glyoxalase system catalases the conversion of methylglyoxal (and other 2-ketoaldehydes) to D-latic acid via teh intrmediate S-D-lactoglutathione.It comprises two enzymes, glyoxalases I and glyoxalases II, and catalytic amount to reduced glutathione.Methylglyoxal inhibits cell growth, while the glyoxalase system by breaking down methylglyoxal may act as a promoter of cell growth.Inhibitors of glyoxalase may serve as possible therapeutic agents against cancer by virtue of their ability to elevate the level of methylglyoxal in the body.

Year

Volume

49

Issue

3

Pages

433-444

Physical description

Contributors

References

Document Type

article

Publication order reference

D.Piskorska

Identifiers

YADDA identifier

bwmeta1.element.element-from-psjc-8ec049de-1911-3c06-830e-6198cbc2cd57
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