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1995 | 49 | 3 | 433-444
Article title

Role glyoxales and methyglyoxal in cell proliferation and differentiation

Title variants
Languages of publication
PL
Abstracts
EN
The glyoxalase system catalases the conversion of methylglyoxal (and other 2-ketoaldehydes) to D-latic acid via teh intrmediate S-D-lactoglutathione.It comprises two enzymes, glyoxalases I and glyoxalases II, and catalytic amount to reduced glutathione.Methylglyoxal inhibits cell growth, while the glyoxalase system by breaking down methylglyoxal may act as a promoter of cell growth.Inhibitors of glyoxalase may serve as possible therapeutic agents against cancer by virtue of their ability to elevate the level of methylglyoxal in the body.
Year
Volume
49
Issue
3
Pages
433-444
Physical description
Contributors
References
Document Type
article
Publication order reference
D.Piskorska
Identifiers
YADDA identifier
bwmeta1.element.element-from-psjc-8ec049de-1911-3c06-830e-6198cbc2cd57
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