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Journal
1999 | 47 | 3-4 | 135-141
Article title

Exoproteinases of the type A in pathogenesis of insect bacterial diseases

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EN
Abstracts
EN
Immune inhibitors produced in infected larvae of Galleria mellonella by such entomopathogens as Pseudomonas aeruginosa, Serratia marcescens and Heterorhabditis bacteriophora effectively blocked in vitro bactericidal activity of insect haemolymph against Escherichia coli D31, both in Galleria mellonella and Pieris brassicae pupae previously vaccinated with Enterobacter cloacae. Even at a trace concentration, the extracellular proteinases, by proteolytic degradation, totally destroyed the activity of cecropin peptides from Galleria and cecropin-like and attacin-family proteins from Pieris, but no ability to destroy antibacterial activity was shown by extracts obtained from Galleria larvae killed by massive doses of bacterial saprophytes. It is suggested that by blocking antibacterial immune response of the host, the proteinases help the bacteria to multiply in the haemolymph, thus they could be considered an important factor in the pathogenesis of bacterial diseases of insects.
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Journal
Year
Volume
47
Issue
3-4
Pages
135-141
Physical description
Contributors
author
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Document Type
ARTICLE
Publication order reference
M. Andrejko, Department of Insect Pathology, Marie Curie-Sklodowska University, Akademicka 19, 20-033 Lublin, Poland
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bwmeta1.element.element-from-psjc-8a0da895-b5c1-352f-a1f4-7cddda31d05d
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