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2003 | 57 | 4 | 369-376
Article title

NOTCH1 receptor: structure and role during T-cell development

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PL
Abstracts
EN
The Notch family are proteins which function both as cell surface receptors and regulators of gene transcription. Notch proteins influence cell-fate decisions during lymphopoesis, neurogenesis and myogenesis. During lymphopoesis Notch1 is implicated in differentiation of lymphoid precursor CLP towards T-cells but not B-cells lineage. In spite of earlier results suggesting involvement of Notch1 in commitment towards alpha beta and gamm a delta or CD4 and CD8 T cell lineage, later experiments didn?t confirm this possibility.
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Year
Volume
57
Issue
4
Pages
369-376
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Contributors
author
References
Document Type
ARTICLE
Publication order reference
B. Gidzinska, Zaklad Immunologii Nowotworow, Instytut Immunologii i Terapii Doswiadczalnej PAN, ul. R. Weigla 12, 53-114 Wroclaw, Poland
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YADDA identifier
bwmeta1.element.element-from-psjc-86d50cc0-42d8-3338-b356-11a351afc44c
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