Full-text resources of PSJD and other databases are now available in the new Library of Science.
Visit https://bibliotekanauki.pl


Preferences help
enabled [disable] Abstract
Number of results
1996 | 56 | 1 | 171-176

Article title

The value of magnetic resonance imaging in diagnosis and monitoring of treatment in multiple sclerosis

Selected contents from this journal

Title variants

Languages of publication



We analysed MR examinations of 227 patients with multiple sclerosis. White matter hyperintensities in brain were found in 270 of them. The most frequently they were found in periventricular white matter (in 100% of cases), in subcortical localization (52.2%) and in the corpus collosum (44.4%). MR examination allows to estimate the activity of the disease on the basis of the presence of oedema around the plaques and their contrast enhancement with gadopentetate dimeglumine (Gd-DTPA). 17.8% of all cases showed the signs of the acute phase of MS. About one-third of all cases were accompanied by cortical brain atrophy (the most often seen in frontal lobes), subcortical brain atrophy was less frequent (one-sixth). In about two-third of all casese the corpus callosum atrophy was found. The analysis of follow-up MR examinations of 83 patients taking part in a double-blind placebo-controlled trial of new immunosupressive drug cladribine showed that patients from pacebo group were more compliant to any changes of plaques. Decrease of the plaques size was found mainly in women. No correlation between patients age and the plaques changes was established.



Document Type


Publication order reference



YADDA identifier

JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.