Studies of immunity in mice immunized with outer membrane proteins of Hafnia

• Authors: Danuta Witkowska , Anna Czarny , Marian Mulczyk
• Languages of publication: EN

Abstracts

EN

Nonspecific protection induced in mice after administration outer membrane proteins of Hafnia alvei against infection with homologue and heterologous bacteria was transferred into other mice with lymphocytes isolated from spleens of mice immunized with outer membrane proteins. It was also found that mice sensitized with outer membrane proteins derived from H. alvei or with living bacteria induced in animals delayed hypersensitivity (DTH) in homologous and heterologous systems. The observed type of hypersensitivity was transferable to normal mice by lymphocytes obtained from donor animals which were previously sensitized with OMP. The experiments revealed that immunity induced with outer membrane proteins of Hafnia alvei is cell-mediated.

Keywords

EN

IMMUNITY; MEMBRANE PROTEIN; MOUSE

Discipline

• IMMUNOLOGY: IMMUNOLOGY

• Publisher: Ludwik Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences
• Journal: Archivum Immunologiae et Therapiae Experimentalis
• Year: 1992
• Volume: 40
• Issue: 2
• Pages: 119-124

Contributors

author

Danuta Witkowska

author

Anna Czarny

author

Marian Mulczyk

• Document Type: article