Role of endothelin-1 in cardiovascular regulation in haemorrhagic shock

• Authors: J. Jochem , J. Josko
• Languages of publication: PL

Abstracts

EN

Endothelin-1 (ET-1), a 21-amino acid polypeptide, produced mainly in endothelial cells is the most potent mammalian vasoconstrictor peptide known. Haemorrhagic hypotension is accompanied by the increase in plasma ET-1 concentration. The significance of this effect, however, is not clear. This paper reviews the causes of the rise in ET-1 plasma concentration and the role of ET-1 in cardiovascular regulation in haemorrhagic shock.

Keywords

EN

ENDOTHELIN-1; HAEMORRHAGIC SHOCK; HEMORRHAGIC SHOCK

Discipline

• EXPERIMENTAL_BIOLOGY_&_MEDICINE: EXPERIMENTAL BIOLOGY & MEDICINE

• Journal: Postępy Higieny i Medycyny Doświadczalnej
• Year: 2000
• Volume: 54
• Issue: 6
• Pages: 835-843

Contributors

author

J. Jochem

author

J. Josko

• Document Type: ARTICLE
• Publication order reference: J. Jochem, Katedra i Zaklad Fizjologii Sl.AM, ul. H. Jordana 19, 41-808 Zabrze, Poland