Proteases of neutrophilic granulocytes

• Authors: W. Roszkowska-Jakimiec , A. Worowska , M. Gacko , T. Maksimowicz
• Languages of publication: PL

Abstracts

EN

The literature referring to proteolytic enzymes of neutrophilic granulocytes was surveyed. Biosynthesis, subcellular distribution, division according to the catalytic site structure, inhibitors and methods used to determine the activity of these enzymes were discussed. The survey included metaloproteases (granulocytic collagenese, gelatinase B), serine proteases (granulocytic elastase, cathepsin G, protease-3), membraneous proteases (aminopeptidase N, aminopeptidase P, neprilisine), cysteine and aspartic cathepsins. The role of these proteases in the pathology and diagnostics of certain diseases was

Keywords

EN

GRANULE; NEUTROPHILIC GRANULOCYTE; PROTEASE INHIBITOR

Discipline

• EXPERIMENTAL_BIOLOGY_&_MEDICINE: EXPERIMENTAL BIOLOGY & MEDICINE

• Journal: Postępy Higieny i Medycyny Doświadczalnej
• Year: 2002
• Volume: 56
• Issue: 1
• Pages: 73-92

Contributors

author

W. Roszkowska-Jakimiec

author

A. Worowska

author

M. Gacko

author

T. Maksimowicz

• Document Type: ARTICLE
• Publication order reference: W. Roszkowska-Jakimiec, Zaklad Analizy Instrumentalnej AM, ul. Mickiewicza 2, 15-230 Bialystok, Poland