In the course of hemorrhagic shock. Here are multidirectional organ changes that result in intensified disjunction of important organs as well as multiorgan insufficiency syndrome. The syndrome is a cause of high post-traumatic mortality. The general inflammatory reaction of intensive ? liver ? lungs ? immunological system increases in a cascadical way and has a significant role in the pathogenesis of the syndrome. Most cells activated as a result of ischemia and reprefusion participate in the phenomenon.