Serum TNF-alpha levels in the neoplasm of patients qualified for surgical treatment
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The aim of the study was to analyze serum tumor necrosis factor alpha (TNF-) levels in different neoplasm types qualified for surgical treatment and to evaluate their possible correlations with circulating immune complexes (CIC), IgG, IgM, and thecomplement (C) compounds: C1 inhibitor (C1i), C3c and C4 levels. Studies were performed in sera from 30 neoplasm patients before surgical treatment and in 10 persons from a control group (CG) with no malignancy. Serum TNF- levels were measured with the Cytogen ELISA kit. Average TNF- levels measured in neoplastic patient groups qualified for surgical treatment were not significantly different from the average TNF- level in the CG group.
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H. Gendek-Kubiak, Division of Cytophysiology, Department of Histology and Embryology, Medical University of Lodz, Narutowicza 60, 90-136 Lodz, Poland