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Journal
1996 | 3 | 34-42
Article title

Recombinant hirudin

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Languages of publication
PL
Abstracts
EN
Hirudin is well known antithrombotic agent with potentially wide application in the clinical treatment of the diseases of circulatory system.In this review the autors discuss biochemical and functional properties of natural hirudins as well as recombinant forms of the protein.The genetic engineering approaches to hirudin expression as well as the methods and techniques of protein isolation and purification are discussed and summarized.We emphasize the most important advantages potentially originationg from the clinical use of hirudin as a specific thrombin inhibitor, and its potential role in clinical practice, particularly in regard to heparin preparations.
Publisher

Journal
Year
Issue
3
Pages
34-42
Physical description
Contributors
author
author
References
Document Type
article
Publication order reference
C.Pietrucha
Identifiers
YADDA identifier
bwmeta1.element.element-from-psjc-76edcfea-40ca-306f-9268-d0325f8fe725
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