Regulation of NF-kB activity

• Authors: J. Siednienko , W.A. Gorczyca
• Languages of publication: PL

Abstracts

EN

Nuclear factor kB (NF-kB) is common proinflammatory transcription factor involved in expression of c.a. 300 different genes. It is usually present in the cytosol as an inactive complex and upon activation translocates into the nucleus. The mechanisms of activation of NF-kB are complex and they involve several different signaling pathways and plethora of proteins. In this minireview we describe the main deciphered as well as suggested mechanisms regulating of NF-kB activity

Keywords

EN

ACTIVATION   NUCLEAR FACTOR   REGULATING  

Discipline

• EXPERIMENTAL_BIOLOGY_&_MEDICINE: EXPERIMENTAL BIOLOGY & MEDICINE

• Publisher: Index Copernicus International; Ludwik Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences
• Journal: Postępy Higieny i Medycyny Doświadczalnej
• Year: 2003
• Volume: 57
• Issue: 1
• Pages: 19-32
• Document Type: ARTICLE
• Publication order reference: W.A. Gorczyca, Instytut Immunologii I terapii Doswiadczalnej PAN ul. R.Weigla 12, 53-114 Wroclaw, Poland