Genes and enzymes taking part in biotransformation of steroid ring structure

• Authors: A. Brzostek , T. Poplawski , Y. Murooka , J. Dziadek
• Languages of publication: PL

Abstracts

EN

Biotransformation of steroid compounds involves two major steps: side chain degradation, which is poorly understood at the genetic level, and the degradation of steroid ring structure, which is better known. This article describes well known molecular mechanisms of ring structure multistep biodegradation. Particular stress is put on the role of cholesterol oxidase, ketosteroid dehydrogenase, ketosteroid isomerase as the best analysed enzymes involved in steroid biotransformation.

Keywords

EN

ENZYME; GENE; RING STRUCTURE; STEROID

Discipline

• BIOTECHNOLOGY: BIOTECHNOLOGY

• Journal: Biotechnologia
• Year: 1998
• Issue: 2
• Pages: 67-85

Contributors

author

A. Brzostek

author

T. Poplawski

author

Y. Murooka

author

J. Dziadek

• Publication order reference: A. Brzostek, Pracownia Genetyki Drobnoustrojow, Centrum Mikrobiologii i Wirusologii PAN, ul. Lodowa 106, 93-232 Lodz, Poland