MELAS as an example of a mitochondrial disease

• Authors: J. Piechota , Mroczek K. Mroczek , K. Mroczek , Bartnik E. Bartnik , E. Bartnik
• Languages of publication: EN

Abstracts

EN

MELAS (mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes) is a disease mainly due to a mutation at position 3243 (A G) in the leucine tRNA gene in mitochondrial DNA. Symptoms of the disorder are complex and the exact pathogenesis is not understood. A review of the literature on the subject is presented.

Keywords

EN

MITOCHONDRIAL DISEASE

Discipline

• GENETICS: GENETICS

• Publisher: Institute of Plant Genetics, Polish Academy of Sciences
• Journal: Journal of Applied Genetics
• Year: 2001
• Volume: 42
• Issue: 3
• Pages: 351-358

Contributors

author

J. Piechota

author

Mroczek K. Mroczek

author

K. Mroczek

author

Bartnik E. Bartnik

author

E. Bartnik

• Document Type: REVIEW
• Publication order reference: E. Bartnik, Department of Genetics, University of Warsaw and Institute of Biochemistry and Biophysics, Polish Academy of Sciences, ul. Pawinskiego 5a, 02-106 Warszawa, Poland, e-mail: [e-mail]