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Journal
1993 | 2 | 105-120
Article title

The application of monoclonal antibodies to medical treatment

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PL
Abstracts
EN
In this review contemporary trends in the application of monoclonal antibodies are presented. There is discussed antibody reengineering for humanization of mouse monoclonal antibodies to avoid anti-globulin reaction of patient. Recent modifications of antibody fragments are also outlined. The most common antigenic structures exposed to antibody attack are characterized. Some aspects of human monoclonal antibody production are briefly described. Three most promising therapeutic antibodies - bispecific antibodies, immunotoxins, and radiolabeled immunoconjugates - are presented.
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Journal
Year
Issue
2
Pages
105-120
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Document Type
article
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YADDA identifier
bwmeta1.element.element-from-psjc-71e844ee-cc5c-318b-add6-73b6fa84bfc1
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