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Journal
2009 | 1 | 81-85
Article title

Recycling of eucaryotic ribosomes

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Languages of publication
EN
Abstracts
EN
Until recently protein biosynthesis has been viewed as a process involving only three steps: initiation of translation, elongation of the nascent polypeptide chain and release of the completed unfolded polypeptide. In recent years fourth step in translation has been distinguished ? it is the recycling of the ribosome. In this process posttermination complexes termed post-TC consisting of ribosomes with deacylated tRNA(s) and mRNA are dissociated with the help of ribosome recycling factor (RRF), elongation factor G (EF-G) and initiation factor 3 (IF3) in Procaryotes. The mechanism of this final step in Eucaryotes was unknown for a long time, but the work of Pisarev et al. sheds a light on splitting 80S ribosomes and preparing them for the next cycle of translation.
Keywords
EN
Publisher

Journal
Year
Issue
1
Pages
81-85
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Contributors
References
Document Type
REVIEW
Publication order reference
Agata Tyczewska, Institute of Bioorganic Chemistry, Polish Academy of Sciences, Noskowskiego St. 12/14, 61-704 Pozna?, Poland
Identifiers
YADDA identifier
bwmeta1.element.element-from-psjc-717fee44-1eed-396f-bb29-16369ea881c0
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