Biochemical aspects of free radical mediated tissue injury
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A radical is any molecule that contains one or more unpaired electrons.Radicals are normally generated in many metabolic pathways.Some of these radicals can exist in free form and subsequentky interact with various tissue components resulting in dysfunction. The potential role oxygen- and xenobiotic- derived free radical in the pathology of several human diseases stimulated extensive research linking the toxity of numerous xenobiotics and disease processes to a free radical machanism.
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