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2000 | 48 | 5 | 389-398
Article title

The role of cytokines in experimental autoimmune encephalomyelitis

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Languages of publication
EN
Abstracts
EN
Experimental autoimmune encephalomyelitis (EAE) is an animal model of the demyelinating disease multiple sclerosis. In EAE cytokines play a critical role in defining the Th1 or Th2 nature of the autoantigen directed immune response, and in propagating and regulating inflammation within the central nervous system. In this review we summarize some of the recent developments in the field of cytokine research that relate to this model of human disease, focusing principally on disease induced with the autoantigens myelin proteolipid protein and myelin oligodendrocyte protein.
Publisher

Year
Volume
48
Issue
5
Pages
389-398
Physical description
Contributors
author
References
Document Type
REVIEW
Publication order reference
E. Bettelli, Center for Neurologic Diseases, Brigham and Women?s Hospital and Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA 02115, USA
Identifiers
YADDA identifier
bwmeta1.element.element-from-psjc-6c05f476-5c54-30b8-a76b-1f14959fa5e7
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