The role of <melatonin> in human physiology and pathology.I.<Circadian rhythm> of <melatonin secretion>.Involvement of melatonin in reproductive physiology.Melatonin and hypothalamic-pituitary-adrenal cortex axis
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This paper summarizes the recent knowledge on the role of <melatonin> in humans. The first part of the present review considers the following aspects: <circardian rhythm> of <melatonin excretion>, <melatonin> in <body fluids>, melatonin influence on <sexual maturation>, changes of melatonin blood concentration during the <menstrual cycle> and <pregnancy>, and the influence of <melatonin administration> on <prolactin concentration>. Current views on the relationship between melatonin and the hypothalamo-pituitary-adrenal cortex axis, as well as on changes of <melatonin concentration> during <hypothyreosis>, and <hyperparathyroidism> are also discussed.
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