DNA microarrays in structural and functional genomics

• Authors: A. Zmienko , L. Handschuh , M. Goralski , M. Figlerowicz
• Languages of publication: PL

Abstracts

EN

DNA microarrays or DNA chips were introduced in the middle nineties and have developed as a very powerful tool for structural and functional analysis of genomes. With thousands to millions of probes deposited on each microarray, it is now possible to perform various kinds of analysis on the genome-wide scale. The basic use of microarrays is gene expression profiling. For this purpose, both one- and two-color labeling methods are used. More sophisticated DNA microarrays allow for analyzing alternative splicing, DNA-protein interactions, chromatine modifications and many more. Currently, DNA microarrays represent an indispensable tool in biology and medicine.

Keywords

EN

DNA CHIP; GENE EXPRESSION; MICROARRAY

Discipline

• BIOTECHNOLOGY: BIOTECHNOLOGY

• Journal: Biotechnologia
• Year: 2008
• Issue: 4
• Pages: 39-53

Contributors

author

A. Zmienko

author

L. Handschuh

author

M. Goralski

author

M. Figlerowicz

• Document Type: REVIEW
• Publication order reference: Agnieszka Zmienko, Instytut Chemii Bioorganicznej, Polska Akademia Nauk, ul. Noskowskiego 12/14, 61-704 Poznan, Poland