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Number of results

Journal

1996 | 4 | 153-166

Article title

Interaction of Antisense oligonucleotides with DNA and proteins studied by fluorescence polarization spectroscopy

Title variants

Languages of publication

EN

Abstracts

EN
In order to evaluate the antisense effects in biological systems, the interaction of antisense molecules with biological substances such as DNAs and human serum proteins was studied by fluorescence depolarization spectroscopy.When an antisense oligonucleotide anchoring fluorescence (F-AS) was mixed with DNAs or proteins, the anisotropy value changed, indicating that antisense oligonucleotides appreciably interact with DNAs and serum proteins, and that such interaction may play important roles on antisense gene regulation.

Journal

Year

Issue

4

Pages

153-166

Physical description

Contributors

author
author
author
author
author
author

References

Document Type

article

Publication order reference

Akira Murakami, Dept. of Polymer Science and Engineering, Kyoto Institute of Technology, Matsugasaki, Sakyo-ku, Kyoto 606, Japan

Identifiers

YADDA identifier

bwmeta1.element.element-from-psjc-64161da9-ac8c-36e0-84c7-119d73e68ac3
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