ACE-inhibitors and atherosclreosis

• Authors: J. Gminski , M. Stajszczyk
• Languages of publication: PL

Abstracts

EN

The activation of the renin-angiotensin system has been proposed as a very important step in the pathogenesis of atherosclerosis. Accordingly, ACE-inhibitors and angiotensin II receptors antagonists showed their ability to reduce the atherosclerotic process in animals. Inhibition of renin-angiotensin system reduces the development of atherosclerotic lesion either in cholesterol-fed animals and in animals after vascular injury. The precise mechanism for this action may depend on the inhibition of other than hypertensive property of angiotensin II.

Keywords

EN

ANGIOTENSIN; ANGIOTENSINOGEN; ARTERIOSCLEROSIS; AT1 RECEPTOR; CORONARY HEART DISEASE; GENETIC POLYMORPHISM; GENETIC PREDISPOSITION; MYOCARDIAL INFARCTION; PRIMARY HYPERTENSION; RENNIN; RENNIN-ANGIOTENSIN SYSTEM

Discipline

• EXPERIMENTAL_BIOLOGY_&_MEDICINE: EXPERIMENTAL BIOLOGY & MEDICINE

• Journal: Postępy Higieny i Medycyny Doświadczalnej
• Year: 1996
• Volume: 50
• Issue: 2
• Pages: 157-171

Contributors

author

J. Gminski

author

M. Stajszczyk

• Document Type: article
• Publication order reference: M.Stajszczyk, ul. Medykow 18, 40-752 Katowice, Poland